pathway

Schmidt's team previously screened a library of more than 58,000 molecules and identified several that interfered with the RAGE-DIAPH1 pathway.

These findings help researchers move closer to uncovering the biological pathways that might be used to lengthen life while avoiding the uncomfortable aspects of current strategies.

She said: "It's about humanity, isn't it? We all believe there's a system there to protect us and when you go in it and you find out it doesn't, it's a very lonely pathway."

Recent research suggests that the gut microbiome may promote CAD through a variety of biological pathways, influencing inflammation and metabolism in ways that impact the arteries.

"It's not easy being in an academy, but it's easier than those who are not in it, as they don't have that pathway," he says.