nonresistant

Working with Valerie Kickhoefer in Rome’s lab, the group then found that the drug-resistant cancer cells generated many more vaults than nonresistant ones, suggesting the structures might sequester or expel chemotherapies.

Because of the study’s small sample size — just eight resistant and four nonresistant trees at each site — Preisser calls it a “proof of concept” that adelgid-resistant trees can be found and propagated.

Because this was a nonresistant “control” tree, she expected an orange infection to spread swiftly from the inoculation site and eventually encircle the small stem.

When a mutation produces resistance to a fungicide, that particular strain will flourish as the nonresistant strains die off.

AMR happens when microbes acquire resistance, mutate or are exposed to an environment where they can develop without the balance provided by nonresistant strains, resulting in their spread.