irritate

It’s a puzzling and irritating gesture that in context sounds like a mistake.

The level of understanding she had of Alani, and Whitaker’s desire to humanize her, made a character who could have been seen as unrelatable, ignorant or even irritating into a delightfully self-aware fan favorite.

These overstimulated immune cells then move toward the dorsal root ganglia -- the sensory nerve hubs that link the limbs to the spinal cord -- and release inflammatory compounds that irritate and damage nerves.

"It irritates the life out of me," she says.

Mosquito bites usually annoy me, but I don’t just feel irritated—I feel confused.