challenge

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

One of the biggest challenges in cancer care is that the same therapy can be highly effective for some patients yet fail entirely for others.

From Science Daily

This discovery not only challenges existing ideas in fundamental physics but may also serve as a kind of universal connector linking electronics, spintronics, and quantum technologies.

From Science Daily

A fortunate man, I had a fulfilling and challenging career as an audio engineer.

From Los Angeles Times

Bonar told me that she was not challenging the sanction but declined to comment on it further.

From Los Angeles Times

Even if they survive such a fight, the cases could be dogged by a series of logistical challenges.

From Salon