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Definitions

challenge

[chal-inj] / ˈtʃæl ɪndʒ /




Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

However, it creates a challenge in cancer therapy because many treatments work by damaging tumor DNA beyond repair.

From Science Daily • May 17, 2026

Although Carano is unlikely to pose a competitive challenge for Rousey, both women are approaching the event more as pioneers than as rivals.

From Los Angeles Times • May 16, 2026

But current Carlsbad officials have sided with Levy—and have hired outside counsel to challenge the commission’s claims.

From The Wall Street Journal • May 16, 2026

That contest is expected in mid-June at the earliest, meaning any formal leadership challenge is likely to be triggered afterwards.

From Barron's • May 16, 2026

She tilts her head, a silent challenge to what I know.

From "Red Flags and Butterflies" by Sheryl Azzam




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