substances

NOUN

entity, element

Synonyms

STRONGEST

item material object stuff texture

STRONG

actuality animal being body bulk concreteness core corpus fabric force hunk individual mass matter person phenomenon reality staple thing

WEAK

something

Antonyms

STRONG

abstract fantasy inanimate nothing nothingness plant

WEAK

poverty

NOUN

essence, meaning

Synonyms

STRONGEST

amount effect meat significance strength stuff subject

STRONG

ABCs basis body bottom burden center core corpus crux drift essentiality focus gist guts heart import innards kernel marrow mass matter nitty-gritty nub pith point purport quintessence sense soul staple tenor theme thrust upshot

WEAK

bottom line brass tacks general meaning gravamen name of the game nuts and bolts sum total virtuality way of it

Antonyms

STRONG

cowardice exterior exteriority fear insignificance nothing nothingness outside periphery surface

WEAK

poverty

NOUN

wealth

Synonyms

STRONG

affluence assets estate fortune means property resources riches worth

Antonyms

STRONG

debt

WEAK

poverty

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Substances that prevent the immune system from being shut down.

From The Wall Street Journal • May 4, 2026

The company said it is cooperating with the Texas attorney general’s office and providing the requested documentation, adding that information on its Restricted Substances program is publicly available on its website External link.

From Barron's • Apr. 13, 2026

One major reason is the 2018 federal decision to remove hemp from the Controlled Substances Act, which allowed hemp-derived CBD to be legally sold and widely distributed.

From Science Daily • Nov. 18, 2025

In March, an investigation by the state Department of Toxic Substances found containers of acetylene, a highly flammable gas, on the plant’s grounds.

From Los Angeles Times • May 20, 2025

Substances in opposite electrical states appear to combine chemically, and the greater the electrical difference the greater the readiness with which chemical combination is effected.

From Heroes of Science Chemists by Muir, M. M. Pattison (Matthew Moncrieff Pattison)