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Definitions

significance

[sig-nif-i-kuhns] / sɪgˈnɪf ɪ kəns /
NOUN
meaning
Synonyms
STRONGEST
connotation implication sense understanding
STRONG
acceptation drift force heart import kicker meat message nitty-gritty nub point purport score signification stuff
WEAK
bottom line intendment name of the game nature of the beast nuts and bolts punch line significancy
Antonyms
STRONG
exterior exteriority outside
WEAK
insignificance meaninglessness triviality unimportance
NOUN
importance
Synonyms
STRONGEST
consequence gravity influence magnitude matter merit prestige relevance virtue weight
STRONG
authority consideration credit excellence import impressiveness moment momentousness perfection pith signification weightiness
Antonyms
STRONGEST
insignificance unimportance weakness
STRONG
disregard disrespect failure imperfection
WEAK
meaninglessness triviality

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The DHX29-driven mechanism could influence important biological processes such as cell differentiation, maintaining cellular balance, and the development of cancer, suggesting wide-ranging significance.

From Science Daily • Apr. 9, 2026

In an interview with AFP, Kutryk discusses the significance of this new chapter of American space exploration:

From Barron's • Mar. 31, 2026

But the significance of these cases runs deeper: They threaten the legal architecture that has allowed Big Tech to reap trillions of dollars in profits with little risk of consequence in court.

From Slate • Mar. 30, 2026

Which fairly raises a few questions about the utility of employing Hegel as a guide to historical significance.

From Salon • Mar. 28, 2026

The fact that the meaning of race may evolve over time or lose much of its significance is hardly a reason to be struck blind.

From "The New Jim Crow" by Michelle Alexander