make it tough for

afflict aggrieve agonize ail bother break bug depress desolate discombobulate disquiet disturb dog eat get grieve harass harry hound hurt injure irk irritate miff nag needle oppress pain peeve perplex pester plague push rack sadden strain strap stress torment torture trouble try vex weigh wound

be on one's case burn up do a number on get to give a hard time nit-pick pick on push buttons tick off

aid appease assist assuage be happy build calm cheer comfort cure delight discourage dissuade fix gladden heal help hide ignore leave alone make happy mend neglect placate please relieve soothe support