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Definitions

senescent

[si-nes-uhnt] / sɪˈnɛs ənt /
ADJECTIVE
aged
Synonyms
STRONGEST
elderly
STRONG
ancient antediluvian antiquated antique gray oldie shot worn
WEAK
age-old been around creaky getting on moth-eaten over the hill passé rusty senior citizen timeworn venerable worse for wear
Antonyms
STRONG
fresh modern new recent up-to-date young
WEAK
unripe youthful
ADJECTIVE
long in the tooth
Synonyms
WEAK
aging getting on getting up in years gray-haired white-haired
ADJECTIVE
obsolescent
Synonyms
WEAK
growing old out-of-date out-of-fashion
ADJECTIVE
senile
Synonyms
WEAK
aged ancient anile decrepit doddering doting enfeebled feeble imbecile in second childhood infirm old shattered sick weak
Antonyms
WEAK
alert well young
NOUN
aging
Synonyms
STRONG
crumbling declining developing fading fermenting maturing mellowing slumping stale waning
WEAK
getting along getting on wearing out

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

In young mice, only about 5% of liver macrophages were senescent.

From Science Daily • Apr. 16, 2026

"Eliminating senescent cells doesn't just slow the fatty liver -- it actually reverses it."

From Science Daily • Apr. 16, 2026

The research team plans to screen for safer compounds that can selectively remove senescent macrophages without harmful side effects.

From Science Daily • Apr. 16, 2026

For years, researchers questioned whether macrophages, the immune cells that patrol the body and clean up debris, could truly become senescent.

From Science Daily • Apr. 16, 2026

In one thin arm, threaded with veins in a kind of senescent bas-relief, was a basket.

From "The Great Santini" by Pat Conroy

Vocabulary lists containing senescent

This Week In Words: August 31–September 6, 2019

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Ancient Wisdom: Synonyms for "Old"

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The Last Cuentista

Want to remember this word for good? Start your learning journey today with our library of interactive, themed word lists built by the experts at Vocabulary.com – we'll help you make the most of your study time!