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Definitions

senescent

[si-nes-uhnt] / sɪˈnɛs ənt /
ADJECTIVE
aged
Synonyms
STRONGEST
elderly
STRONG
ancient antediluvian antiquated antique gray oldie shot worn
WEAK
age-old been around creaky getting on moth-eaten over the hill passé rusty senior citizen timeworn venerable worse for wear
Antonyms
STRONG
fresh modern new recent up-to-date young
WEAK
unripe youthful
ADJECTIVE
long in the tooth
Synonyms
WEAK
aging getting on getting up in years gray-haired white-haired
ADJECTIVE
obsolescent
Synonyms
WEAK
growing old out-of-date out-of-fashion
ADJECTIVE
senile
Synonyms
WEAK
aged ancient anile decrepit doddering doting enfeebled feeble imbecile in second childhood infirm old shattered sick weak
Antonyms
WEAK
alert well young
NOUN
aging
Synonyms
STRONG
crumbling declining developing fading fermenting maturing mellowing slumping stale waning
WEAK
getting along getting on wearing out

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

When compared with autopsy samples from individuals without epilepsy, the tissue from TLE patients showed a five-fold increase in senescent glial cells.

From Science Daily • Dec. 25, 2025

"Our hope is that senotherapy, which involves using medications to remove senescent, or aging cells, could potentially minimize the need for surgery and/or improve outcomes after surgery."

From Science Daily • Dec. 25, 2025

Researchers at Mayo Clinic, writing in the journal Aging Cell, describe a new method for labeling senescent cells.

From Science Daily • Dec. 14, 2025

However, its discovery suggests that aptamers may help identify features unique to senescent cells.

From Science Daily • Dec. 14, 2025

In one thin arm, threaded with veins in a kind of senescent bas-relief, was a basket.

From "The Great Santini" by Pat Conroy

From Roget's 21st Century Thesaurus, Third Edition Copyright © 2013 by the Philip Lief Group.