critical

Combined with clampdowns on protests, critical journalists and academics, she concludes: "I think these point in a non-peaceful direction."

Normally, alpha-synuclein's natural or "native state" is like a flexible strand, but when active it shapes itself into a helix, which is critical for its function in binding and transporting parcels of dopamine.

“Mike and Pam’s unwavering leadership and commitment to this business has been critical to our success this year,” he wrote.

They too were critical of the prime minister – but for different reasons.

NHS England's Chief Nursing Officer Duncan Burton told the inquiry its response to safeguarding did not stop throughout the pandemic despite staff being diverted to critical services.