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most significant





Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

“The University of California is facing the most significant disruption to our research enterprise in our history,” Milliken said, pointing to federal funding cuts.

From Los Angeles Times • May 6, 2026

Perhaps the most significant factor working against Monolithic is the price.

From Barron's • May 1, 2026

The move, initially joined by Morocco and Bahrain, was the most significant break in Israel’s regional isolation since Egypt made peace half a century ago.

From The Wall Street Journal • Apr. 30, 2026

He described it as "a state visit for the ages, the most significant since his grandfather George VI's visit in 1939 on the eve of the Second World War".

From BBC • Apr. 29, 2026

I wish my essay could have been about the most significant event in my life; how my family immigrated to America.

From "The Freedom Writers Diary" by The Freedom Writers