Thesaurus.com
Dictionary.com
Showing results for spleen. Search instead for spleenier.
Definitions

spleen

[spleen] / splin /
NOUN
peevishness, spite
Synonyms
STRONGEST
ill humor ill temper peevishness
STRONG
anger choler depression dislike grudge hatred hostility ire malice maliciousness meanness melancholy nastiness rancor resentment spite spitefulness wrath
WEAK
despitefulness
Antonyms
STRONG
cheer friendliness happiness joy kindness liking love loving sympathy
WEAK
good humor

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Problems were seen in iron recycling within the spleen and in the normal functioning of the lungs, intestines and kidneys.

From Science Daily • Mar. 1, 2026

Kala-azar is spread by sandflies and is one of the most dangerous neglected tropical diseases, with a fatality rate of 95 percent if untreated, causing fever, weight loss, and enlargement of the spleen and liver.

From Barron's • Feb. 8, 2026

Further CT and MRI scans revealed an enlarged spleen and, in September 2025, she was diagnosed with myelofibrosis.

From BBC • Jan. 26, 2026

Soon after, he was treated for an enlarged spleen.

From The Wall Street Journal • Nov. 5, 2025

Diego chuckled like a ruptured spleen was hilarious.

From "We Are the Ants" by Shaun David Hutchinson

From Roget's 21st Century Thesaurus, Third Edition Copyright © 2013 by the Philip Lief Group.