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He is set to make the remarks at his party's annual conference, his second in charge after reclaiming the leadership last year.

San Francisco Mayor Daniel Lurie’s office offered a more muted response, touting the mayor’s efforts to boost public safety in general, but declining to directly address Benioff’s remarks.

AMD did not immediately respond to a request for comment about the benchmark results and Nvidia’s remarks.

Financial markets dropped in the wake of the remarks, with the S&P 500 down roughly 1.4% in late morning trade in New York.

His remarks reflect a rapid shift from just months ago in how business leaders discuss the potential human cost of the technology.