malignant

Glioblastoma develops from astrocytes, a type of brain cell, and is the most common malignant brain tumor, affecting about three in every 100,000 people in the U.S.

This combination successfully triggered necroptosis in malignant B cells and produced a powerful immune response that completely eliminated leukemia in a preclinical model.

"Bone marrow or stem cell transplants are most commonly used in blood cancers, in which the bone marrow is full of malignant cells and patients have no other options," said Czechowicz.

It also highlights the value of naturally removing compromised stem cells through "senolysis," a biological process that helps prevent cancer by sacrificing cells that could otherwise become malignant.

Many malignant tumors are described as immune-suppressive or "immune cold" because the body's defenses fail to recognize them as threats.