challenges
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
Scientists have uncovered an unexpected way the immune system can attack cancer, a finding that challenges a long-standing principle in immunology and could lead to new approaches for cancer treatment and bone marrow transplantation.
From Science Daily • Jun. 4, 2026
But throughout all the challenges, Mexican President Claudia Sheinbaum has remained resolutely upbeat.
From BBC • Jun. 4, 2026
This outbreak wasn’t detected earlier because of a combination of diagnostic and security challenges.
From The Wall Street Journal • Jun. 3, 2026
Analysts note that Section 301 tariffs have been less vulnerable to court challenges.
From Barron's • Jun. 3, 2026
In effect, the political institutions and the very authority of the federal government were too new and ill-formed to cope effectively with the foreign and domestic challenges facing the new nation.
From "Founding Brothers: The Revolutionary Generation" by Joseph J. Ellis
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