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difficile
adjective as in difficult
Strongest matches
adjective as in hard
Strongest matches
Weak matches
- backbreaking
- bothersome
- burdensome
- demanding
- distressing
- effortful
- exacting
- fatiguing
- formidable
- grinding
- hairy
- herculean
- intricate
- involved
- irksome
- knotty
- labored
- laborious
- mean
- merciless
- murder
- onerous
- operose
- rigorous
- rugged
- scabrous
- severe
- slavish
- sticky
- strenuous
- tiring
- toilful
- toilsome
- unsparing
- uphill
- uphill battle
- wearing
- wearisome
- wearying
Example Sentences
Faecal transplants – also known as a trans-poo-tion - are already approved for treating severe diarrhoea caused by Clostridium difficile bacteria.
But scientists noticed hints that faecal transplants for C. difficile also seemed to get rid of superbugs.
The researchers are currently working on modifying the system to help combat Clostridioides difficile, commonly referred to as C. diff, a bacterium that can cause diarrhea and colitis, among other symptoms.
The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture.
FMT has a 90% cure rate for C. difficile infection.
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From Roget's 21st Century Thesaurus, Third Edition Copyright © 2013 by the Philip Lief Group.
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