detrimental

adverse bad badder damaging deleterious destructive destructive harmful hurtful ill incommodious inconvenient inexpedient injurious malicious malign mephitical mischievous more adverse more negative more pestilent more pestilent more pestilential more poison more poisonous more poisonous most pestilent most pestilent most pestilential most poison most poisonous most poisonous negative noxious pernicious pestilent pestilent/pestilential poison/poisonous poisonous prejudicial toxicant unhealthful unhealthy unwholesome