refractory

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The Food and Drug Administration has accepted a biologics license application for anito-cel as a fourth-line treatment for patients with relapsed or refractory multiple myeloma.

From Barron's • Feb. 23, 2026

Food and Drug Administration is reviewing Arcellx’s application seeking approval of anito-cel as a fourth-line treatment for patients with relapsed or refractory multiple myeloma, with a decision expected by the end of the year.

From The Wall Street Journal • Feb. 23, 2026

"By targeting tumor macrophages, we've shown that it can be possible to eliminate cancers that are refractory to other immunotherapies."

From Science Daily • Jan. 30, 2026

He said the medical cause of Benn's death was "refractory cardiogenic shock due to taxane alkaloid poisoning, following ingestion of yew tree berries and leaves".

From BBC • Dec. 4, 2023

Then in the Clarkston area of Washington the insects became refractory — they were harder to kill than in the orchards of the Wenatchee and Yakima valleys and elsewhere.

From "Silent Spring" by Rachel Carson