refractory

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The Food and Drug Administration has accepted a biologics license application for anito-cel as a fourth-line treatment for patients with relapsed or refractory multiple myeloma.

From Barron's • Feb. 23, 2026

Food and Drug Administration is reviewing Arcellx’s application seeking approval of anito-cel as a fourth-line treatment for patients with relapsed or refractory multiple myeloma, with a decision expected by the end of the year.

From The Wall Street Journal • Feb. 23, 2026

This refractory metal-based material, in whose discovery Dr. Alexander Kauffmann, now professor at the Ruhr University Bochum, played a major role, exhibits properties never seen before.

From Science Daily • Oct. 23, 2025

He said the medical cause of Benn's death was "refractory cardiogenic shock due to taxane alkaloid poisoning, following ingestion of yew tree berries and leaves".

From BBC • Dec. 4, 2023

Sometimes this short, straight-backed young girl hummed under her breath, or sang, while she hoed the com or tugged on the reins when a refractory mule refused to budge.

From "Harriet Tubman: Conductor on the Underground Railroad" by Ann Petry