refractory

They said their blood sugar readings were refractory, meaning they kept coming back despite being given glucose, whereas naturally-occurring hypoglycemia can be easily corrected with a treatment such as a sugary drink.

From BBC ● Sep. 25, 2026

Food and Drug Administration is reviewing Arcellx’s application seeking approval of anito-cel as a fourth-line treatment for patients with relapsed or refractory multiple myeloma, with a decision expected by the end of the year.

From The Wall Street Journal ● Feb. 23, 2026

The Food and Drug Administration has accepted a biologics license application for anito-cel as a fourth-line treatment for patients with relapsed or refractory multiple myeloma.

From Barron's ● Feb. 23, 2026

"By targeting tumor macrophages, we've shown that it can be possible to eliminate cancers that are refractory to other immunotherapies."

From Science Daily ● Jan. 30, 2026

So Meg wrestled alone with the refractory sweetmeats all that hot summer day, and at five o’clock sat down in her topsy-turvey kitchen, wrung her bedaubed hands, lifted up her voice and wept.

From "Little Women" by Louisa May Alcott

U.S. and European companies have been recently investing in developing synthetic graphite as demand from the EV sector is surging for this soft form of carbon, which until recently was mainly used for steelmaking refractories.

From Reuters ● Oct. 20, 2023

It boasted that it was the world's No. 1 producer of aluminum, tinplate, refractories, plumbing fixtures, lifting jacks, air brakes.

From Time Magazine Archive

On arriving at Saint-Savin, the women Lechantre and Bryond heard of the arrest of Bourget, that of the driver of the diligence, and that of the two refractories.

From The Brotherhood of Consolation by Katharine Prescott Wormeley

Allain knew where to find men; twenty-five leagues from Caen, in the department of La Manche, some way from any highroad, is situated the village of La Mancellière, whose men were all refractories.

From The House of the Combrays by G. Le Notre

Thus purged of a very few refractories and inefficients, the ship's company was a happy, loyal and healthy crew, of whom the commander was justifiably proud.

From The Life of Captain Matthew Flinders by Ernest Scott