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of great consequence

ADJECTIVE
grave
Synonyms
STRONG
acute fell heavy killing major pressing threatening
WEAK
afflictive consequential critical deadly destructive dire exigent fatal grievous hazardous important life-and-death momentous ominous perilous serious severe significant ugly urgent vital weighty
Antonyms
STRONG
insignificant little small trivial unimportant
WEAK
cheerful frivolous funny happy inconsequential ridiculous silly

From Roget's 21st Century Thesaurus, Third Edition Copyright © 2013 by the Philip Lief Group.