alienate

He's in danger of alienating the fans going after them like that.

Implementing the agreement is likely to alienate his right-wing allies in the government, including extremist figures such as Israeli Finance Minister Bezalel Smotrich, who has called for Gaza to be emptied of Palestinians.

Some employers are trying to bring workers together without alienating or uprooting them.

Similarly, do what you want with Bud Light and Cracker Barrel, but you’re the one alienating and disaffecting an entire swath of customers.

The deal might risk alienating OpenAI’s main supplier at a time when Nvidia has no problem selling every chip it can make.