have on

The reaction of financial markets has been closely watched in the run-up and aftermath of the Budget giving the impact the tax and spending policies could have on UK borrowing costs.

"Looking back now, I didn't realise what impact it would have on the people of Manchester."

"Because he wants more, the team knows him better, his role is growing around the team. The impact he has on the team, it's huge."

Maybe this is her chance to bid adieu to the beautiful life she had on Earth with Larry and see what the future holds with Luke.

Since choline supports the brain and liver, long-term shortages may heighten vulnerability to metabolic stress and intensify the effect obesity has on the brain.