ampicillin

The strain typically resists four major antibiotics: ampicillin, streptomycin, sulfisoxazole and tetracycline.

Human and wildlife E. coli isolates also had similar levels of resistance to the same antibiotics—most commonly ampicillin, doxycycline, streptomycin, tetracycline, and trimethoprim/sulfamethoxazole.

Other drugs that the pathogen has overcome in the past include ampicillin, streptomycin and tetracycline.

In the United States, most Shigella is already resistant to the antibiotics ampicillin and trimethoprim/sulfamethoxazole.

To see if antibiotics might have had a damaging effect on the heart, Orihuela's team infected mice with bacterial pneumonia and gave them high doses of the antibiotic ampicillin when heart lesions appeared.