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That’s because it’s prone to introducing unexpected mutations that are hard to spot, and it can generate embryos with a mixture of edited and unedited cells.
Gene editing might be an option when 25 percent or fewer of a couple’s embryos would be free of the disease-causing mutation.
When geneticists need to understand what genes do, they can create laboratory mice with “knockout” mutations and see whether and how the animals cope with the loss.
Without sex we’d have a situation where mitochondrial mutations accumulate much faster and the nucleus could not come up quickly enough with co-adapted mutations.
Dowling’s theory predicts that the faster the mitochondrial mutation rate is, the more often the members of that species will need to have sex.
Some rare variants within a group may have mutations that change how those viruses work, including how they infect cells, Garcia de Jesus says.
The advance paves the way for one day fixing mutations in mitochondria.
Such a mutation evolved at least 10 times in mammal evolution.
Nor is it difficult to discover some of the circumstances that tended to bring about this radical mutation of policy.
Do species change by the gradual elimination of the unfit, or do they change by sudden leaps, the "mutation" theory of de Vries?

WORDS RELATED TO MUTATION

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