mid-14c., enspiren, "to fill (the mind, heart, etc., with grace, etc.);" also "to prompt or induce (someone to do something)," from Old French enspirer (13c.), from Latin inspirare "inflame; blow into" (see inspiration), a loan-translation of Greek pnein in the Bible. General sense of "influence or animate with an idea or purpose" is from late 14c. Also sometimes used in literal sense in Middle English Related: Inspired; inspires; inspiring.