inflammation

The brief bursts of inflammation that the body once used to fight infection can linger.

In contrast, when the team removed CD28 from this rare group of microglia, inflammation rose sharply and plaques associated with Alzheimer's developed more quickly.

The procedure proved safe, with no serious inflammation or tumor growth reported in any of the patients.

The researchers then gave the microspheres orally to mice with varying levels of colitis, ranging from no disease activity to severe inflammation.

Their previous studies demonstrated that this pathway can drive pain after surgery and inflammation in mouse models.