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Definitions

herpes simplex

[hur-peez sim-pleks] / ˈhɜr piz ˈsɪm plɛks /
NOUN
canker sore
Synonyms
WEAK
canker cold sore fever blister herpes labialis lesion oral herpes
NOUN
cold sore
Synonyms
WEAK
canker canker sore fever blister herpes labialis lesion oral herpes
NOUN
sexually transmitted disease
Synonyms
STRONGEST
AIDS acquired immune deficiency syndrome gonorrhea herpes syphilis the clap venereal disease
WEAK
HIV SIDA STD VD chancroid chlamydia clap crab louse crabs genital herpes genital warts scabies social disease tabes dorsalis

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

In Fayetteville, North Carolina, in 2020, as in other military towns across the U.S., rates of sexually transmitted infections like syphilis, herpes simplex and HIV are among the highest in the country.

From Salon • Jul. 20, 2025

It’s been associated with infections such as the herpes simplex virus and Epstein-Barr virus, as well as Lyme disease and autoimmune disorders.

From Seattle Times • Apr. 26, 2024

Remarkably, people lacking functional UNC93B1 are prone to viral infections with a severe course, such as herpes simplex virus encephalitis and severe COVID-19, highlighting the essential role of UNC93B1 for a healthy immune system.

From Science Daily • Jan. 14, 2024

Deaths caused by HSV-1 - herpes simplex 1 - are almost unheard of in healthy people.

From BBC • Jul. 26, 2023

Rather than homing in on, say, the relationship between herpes simplex infections and Alzheimer’s disease—a recent focus in her own field—“this research broadens that scope to look at different viruses and more neurodegenerative diseases.”

From Science Magazine • Jan. 19, 2023