Definitions

degenerative

[dih-jen-er-uh-tiv, -uh-ray-tiv] / dɪˈdʒɛn ər ə tɪv, -əˌreɪ tɪv /

ADJECTIVE

tending to diminish in quality

Synonyms

STRONGEST

backward deteriorating regressive retrogressive

STRONG

declinatory depressive dwindling frittering

WEAK

deleterious

Antonyms

STRONGEST

improving progressive

WEAK

expanding growing

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

degenerative

CTE, which stands for chronic traumatic encephalopathy, is a degenerative brain disease involving the buildup in the brain of “tau” proteins associated with forms of dementia such as Alzheimer’s.

From MarketWatch ● Sep. 30, 2026

I had vaguely heard about MS but I really knew nothing about the degenerative disease.

From BBC ● Aug. 28, 2026

At least a quarter of National Football League players may end up with a degenerative brain disease, according to a new study published Tuesday that lays bare the extreme toll of America's favorite sport.

From Barron's ● Aug. 25, 2026

For now, regular cardiology care remains the practical priority for people with degenerative mitral regurgitation.

From Science Daily ● Jul. 12, 2026

It produces degenerative changes in the liver and kidneys.

From "Silent Spring" by Rachel Carson

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