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Definitions

degenerative

[dih-jen-er-uh-tiv, -uh-rey-tiv] / dɪˈdʒɛn ər ə tɪv, -əˌreɪ tɪv /


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Petrou was diagnosed with retinitis pigmentosa, a degenerative disorder that leads to vision loss, at age 18.

From The Wall Street Journal • Mar. 12, 2026

That diagnosis was subsequently changed to one of progressive supranuclear palsy, a degenerative brain disease with similar symptoms.

From BBC • Feb. 17, 2026

Also posted to the “We’re Not Gonna Take It” singer’s Instagram account, the statement said that Snider “has had several surgeries over the years” to help manage his degenerative arthritis.

From Los Angeles Times • Feb. 6, 2026

Li, who suffers from a genetic degenerative condition that progressively weakens muscles, relies on a ventilator permanently connected to his windpipe to breathe, but grows celery with the help of his 62-year-old mother.

From Barron's • Jan. 29, 2026

Dr. Darwin was now in a wheelchair, Bessy was stuck in a fog, and Josiah was sinking from either a stroke or a degenerative neurological disease.

From "Charles and Emma: The Darwins' Leap of Faith" by Deborah Heiligman