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Definitions

degenerative

[dih-jen-er-uh-tiv, -uh-rey-tiv] / dɪˈdʒɛn ər ə tɪv, -əˌreɪ tɪv /


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

A handful were posthumously diagnosed with chronic traumatic encephalopathy, the progressive, degenerative brain disease found in people with a history of repetitive head impacts.

From Los Angeles Times • Mar. 23, 2026

Petrou was diagnosed with retinitis pigmentosa, a degenerative disorder that leads to vision loss, at age 18.

From The Wall Street Journal • Mar. 12, 2026

The researchers say these findings challenge the routine practice of recommending exercise as the first line treatment for reducing pain and improving mobility in people with this degenerative joint disease.

From Science Daily • Feb. 25, 2026

The degenerative brain disease can only be diagnosed definitively after death, and has been linked to dementia.

From BBC • Feb. 10, 2026

The distinguished historian Tony Judt, who died in mid-2010 of motor neuron disease, used it to compose essays after his degenerative disease robbed him of the ability to move.

From "Words Like Loaded Pistols" by Sam Leith