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Definitions

degenerative

[dih-jen-er-uh-tiv, -uh-rey-tiv] / dɪˈdʒɛn ər ə tɪv, -əˌreɪ tɪv /


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

CTE is a degenerative brain disease that has been found in people exposed to repetitive head trauma; it can be diagnosed only after death.

From Los Angeles Times • Apr. 7, 2026

Petrou was diagnosed with retinitis pigmentosa, a degenerative disorder that leads to vision loss, at age 18.

From The Wall Street Journal • Mar. 12, 2026

Li, who suffers from a genetic degenerative condition that progressively weakens muscles, relies on a ventilator permanently connected to his windpipe to breathe, but grows celery with the help of his 62-year-old mother.

From Barron's • Jan. 29, 2026

Osteoarthritis is a degenerative joint disease that affects about one in five adults in the United States and generates an estimated $65 billion each year in direct health care costs.

From Science Daily • Jan. 20, 2026

I told her that I have chronic, degenerative, relapsing-remitting inflammobetigoitis.

From "Liar, Liar" by Gary Paulsen