chronic fatigue syndrome

NOUN

disorder involving extreme fatigue and weakness

Synonyms

WEAK

chronic fatigue and immune dysfunction syndrome fatigue disease fatigue syndrome myalgic encephalomyelitis post-viral fatigue syndrome postviral syndrome yuppie flu

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

ME, sometimes referred to as chronic fatigue syndrome, is a chronic and complex multi-system condition.

From BBC • Mar. 22, 2026

Healthy individuals had more of these bacteria than people with conditions such as inflammatory bowel disease, obesity, and chronic fatigue syndrome.

From Science Daily • Feb. 14, 2026

“You’re a kid and you have no authority over anyone,” said Lily, who has POTS, EDS, chronic fatigue syndrome, and chronic pain.

From Slate • Sep. 15, 2025

It is similar to chronic fatigue syndrome and can range from mild to debilitating.

From Los Angeles Times • Dec. 18, 2024

By giving the condition a name like "lymphoma" or "melanoma", "chronic fatigue syndrome" "Epstein-Barr syndrome" or "AIDS," "systemic yeast infection", "hepatitis" or what have, people think the doctor then understands their disease.

From How and When to Be Your Own Doctor by Solomon, Steve