athwart

Caivano elaborated on Washington's various interventionist economic policies, including a number of legislative and executive measures that were initially very unpopular because they seemed to run athwart the notion of a government with limited power.

Leaders decided to stand athwart a liberalizing Orange County instead of adapt.

“If you are opening a Mexican restaurant on Melrose in the 1970s, you are basically standing athwart the past and future of Mexican food in Los Angeles,” he said.

There’s more, of course, in the vein of those coming athwart of fate.

Still, some of those standing athwart Santos’ defenestration yelling “Stop!” — or at least “Think this through” — make good points.