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Until recently, however, scientists did not fully understand how deeply this connection ran.

This disturbance alters how and when hundreds of genes switch on and off, changing key processes that help the brain function properly.

Samples were collected every two hours over a full 24-hour period to track how gene expression changed across the circadian cycle.

"Ultimately, we hope to learn how to optimize the circadian system to prevent amyloid accumulation and other aspects of Alzheimer's disease."

"I think there is no easy route as an artist but you learn as you go and that's how you hone your skills."