He wears the look of one who is gnawed with envy, and he heaves the sigh of despair.
He was seized with fear for what he might do in his despair.
Hope looked round in despair, then glanced at her own disordered garments.
True, we have come far from the days of stagnation and despair.
All the despair in Dick's face, though it wrung his heart, could not move him.